18 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Destruction • Abnormal ... Congenital • Factor ... Deficiency • Factor ... #Causes #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PT (INR) - Bleeding ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Consumption of Clotting Factors ... Treat primary cause ... - APTT < 1.5 x normal ... #diagnosis #causes ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... factor == NORMAL ... intravascular coagulation ... discern these causes ... Differential #Diagnosis #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Causes include : ... Pre-analytical cause ... amyloidosis #Abnormal ... #differential #hematology ... #coagulation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Jcortesizaguirr #Abnormal ... #differential #hematology ... #coagulation
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
• Consistent bleeding ... study (aPTT may be normal ... in mild cases) ... antigen (vWF:Ag) are normal ... Management #treatment #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... hemorrhage, while under-coagulation ... #management #algorithm ... #medications #table ... decisionaid #cardiology #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... deficiency - Abnormal ... Complete blood count coagulation ... #Causes #dermatology
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
ecchymosis) is caused ... are typical of coagulation ... factor deficiencies ... Von Willebrand factor ... Measurement of coagulation