15 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... Incr IGF1 • Bone ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... GH excess after ... signs #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... • GH stimulates ... (Lanreotide) ± GH ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
absorption ↑ bone ... Hypophosphatemia: ↑ bone ... Calcium #Phosphorus #pathophysiology ... #endocrinology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Cushing's Disease • GH ... Chemotherapy • Bone ... Diagnosis #Algorithm #endocrinology
Rachitic Rosary of Rickets on Physical Exam

Bead-like prominences of bone are seen at the costochondral joints.
prominences of bone ... PhysicalExam #clinical #video ... VitaminD #deficiency #endocrinology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
easily/weakness, Bone ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
following order; GH ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Thyroid Function Pathway 

Hypothyroidism is a very common condition! Here's a repost of the pathway that
T4 is low, the body ... Thyroid #Pathway #Pathophysiology ... #Endocrinology
Calcium homeostasis is a process controlled by chiefly by hormones vitamin D and PTH. 
Vitamin D
and stimulating bone ... #Pathophysiology ... #Endocrinology