12 results
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
of Diabetic Ketoacidosis ... primary anabolic hormone ... counterregulatory hormones ... #Pathophysiology ... #Endocrinology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
Parathyroid Hormone ... absorption ↑ bone ... #Parathyroid #Hormone ... Calcium #Phosphorus #pathophysiology ... #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
common), growth hormone ... ) the anterior hormones ... most essential hormones ... the order the hormones ... Loss of pituitary hormones
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth Hormone ... (GH) Growth Hormone ... Incr IGF1 • Bone ... activates lipolysis Signs ... #pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
ACTH -> Decr Sex Hormones ... -> Reduced Bone ... Formation, Increased Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms
Hypercalcemia - Hormones and Pathophysiology  
Calcitriol:
 • Bones: Enhances mineralization
 • GI Tract: ↑ Ca2+
Hypercalcemia - Hormones ... and Pathophysiology ... : • Bones: ↑ Bone ... Hypercalcemia #Hormones ... #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... share the same pathophysiology ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Calcium homeostasis is a process controlled by chiefly by hormones vitamin D and PTH. 
Vitamin D
by chiefly by hormones ... and stimulating bone ... #Pathophysiology ... #Endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology ... #diabetes
Woltman's sign of hypothyroidism- ...At the time of presentation, a physical examination was notable for the
Woltman's sign of ... see source for video ... )...Woltman’s sign ... anorexia nervosa, diabetes ... received thyroid hormone