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diagnosis management differential hematology syndrome neurology gastroenterology ibs irritable treatment acute algorithm als amyotrophic anemia aplastic cancer cauda caudaequina classification
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... injury - Loss of bowel ... Causes: 1. ... below lesion) • Bowel ... Muscle twitching (fasciculations
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Oncologic Emergencies ... neutrophil count < 500 cells ... Epidural Spinal Cord ... Constipation • Nausea ... Hyponatremia • Nausea
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
weakness, bladder/bowel ... meninges in spinal cord ... nerve roots Spinal Cord ... abnormalities, bowel ... • Caused by immune
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
alterations, and bowel ... - Autonomic: Bowel ... Bilateral signs and/or symptoms ... Pleocytosis > 100 cells ... • Infectious causes
Irritable Bowel Syndrome (IBS) - Management Global IBS Symptoms: - Limited trial low FODMAP diet
Irritable Bowel ... Management Global IBS Symptoms ... Rifaximin- up to 3 courses ... ♀ with severe symptoms ... intestinal epithelial cells
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Irritable Bowel ... last 3 months + symptom ... Rifaximin- up to 3 courses ... intestinal epithelial cells ... IBS #Irritable #Bowel
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
multiple spinal cord ... - Causes progressive ... Muscle twitching (fasciculations ... BULBAR: Tongue fasciculations ... Common Symptoms
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... disturbance • Bladder, bowel ... - Emergency Causes ... Diagnosis: • Spinal cord
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... -> AML: Blast crises ... Leukemia #Hematology #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... number of CD34+ cells ... number of CD34+ cells ... • Improve the symptoms ... Aplastic #Anemia #oncology
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