12 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... and progressive fibrosis ... : ILD (interstitial ... lung disease), ... #rheumatology #
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... lupus. ... ConnectiveTissueDiseases #ILD ... Comparison #Table #Pulmonary ... #Rheumatology #
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... activity Anti-Ro/SSA ... Treatment: • Mild ... diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
or scleroderma (SSc ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... Fibrosis, Multiple ... ANA #patterns #rheumatology
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
: • Systemic sclerosis ... Polymyositis-dermatomyositis, Lupus ... • Idiopathic pulmonary ... fibrosis (IPF), ... #differential #pulmonary
Management of interstitial lung disease (ILD)-associated with systemic sclerosis (SSc)

Therapeutic indication: absolute decline in FVC >10%
interstitial lung disease ... (ILD)-associated ... with systemic sclerosis ... #pulmonary #indications ... management #treatment #algorithm
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Interstitial Pneumonia - fibrosis ... Rheumatoid Arthritis, Systemic ... Lupus and Scleroderma ... Amy Chung, MD, MSc ... #ILD #Causes #Differential
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Differential Diagnosis Algorithm ... athletic training, Pulmonary ... Structural: Celiac disease ... Tropical sprue, IBD ... #ferritin #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... • Prolidase deficiency ... CNS • Headache, mild ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Anti-ENA - Rare (SSA ... Prognosis: Usually mild ... months to years) Systemic ... Evolution: Chronic disease ... comparison #table #rheumatology