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diagnosis differential treatment symptoms syndrome lupus sle stills adultonset aosd arthritis comparison dermatology erythematosus hepatology rheumatoid sclerosis table vasculitis workup
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... and progressive fibrosis ... : ILD (interstitial ... lung disease), ... Scleroderma #SSc #rheumatology
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Rheumatoid Arthritis Summary ... Rheumatoid Nodules, Pulmonary ... Disease and ILD ... RA #diagnosis #rheumatology ... #signs #symptoms
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... : Diffuse skin disease ... , Pulmonary fibrosis ... (~93-95%), Pulmonary ... Autoantibodies #diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... arthritis SLE : systemic ... ConnectiveTissueDiseases #ILD ... Comparison #Table #Pulmonary ... #Rheumatology #
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
- Summary Antinuclear ... Treatment: • Mild ... Erythematosus #SLE #Summary ... #diagnosis #rheumatology ... #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Summary • Epidemiology ... Evolution: Chronic disease ... #SLE #lupus #Systemic ... #Summary #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... solid cancers • Systemic ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
• Homogeneous: Systemic ... ) • Speckled: Systemic ... , Interstitial Pulmonary ... Fibrosis, Multiple ... ANA #patterns #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
highly inflammatory disease ... Adult-onset Still disease ... of underlying disease ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... episode (30%) Systemic ... AdultOnset #Stills #Disease ... #AOSD #rheumatology ... #diagnosis #management
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