20 results
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
- Comparison - ... >90% of total skin ... #TABLE #DRESS # ... #Erythroderma #Dermatology ... #Emergency #Differential
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Groups of Cutaneous Drug ... Raised off of the skin ... lasts > 24h • Fine ... #Reactions #dermatology ... #clinical #comparison
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
or fluid-filled lesions ... anti-convulsant or sulfa-drug ... - Skin pain - ... #Diagnosis #Dermatology ... Targetoid #Algorithm #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... lesions that result ... #Diagnosis #hematology ... #nonpalpable #dermatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Drugs 5. ... within one hour or longer ... lesions - Wheals ... Urticaria #diagnosis #rheumatology ... #comparison #table
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
macule and papule (Table ... febrile have a wide differential ... with either a drug ... have a broader differential ... #Diagnosis #Dermatology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Pustular Skin Lesions ... Burrows between fingers ... illness • Drug ... #Lesions #Differential ... #Diagnosis #Dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Skin involvement ... Resolution > 15 days Differentials ... DRESS #Syndrome #dermatology ... #diagnosis #management
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... lesions, or localized ... immunocompromised host Drug ... #Diagnosis #comparison ... #table #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Intravenous Drug ... Pregnancy • Drugs ... Testosterone - Coumadin skin ... atherosclerotic lesions ... pathophysiology #hematology