13 results
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
Early diagnosis ... lethal cardiac complications ... Disease #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... / Symptoms / Complications ... seizure, primitive reflexes ... #diagnosis #signs ... #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... / Symptoms / Complications ... of normal leg reflexes ... pathophysiology #diagnosis ... #symptoms #signs
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... bladder and rectal reflex ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Other brainstem syndromes ... pain • Extra-CNS complications ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
, Mild sensory symptoms ... or signs, Cranial ... nervous system signs ... except in Miller Fisher ... #neurology #neuropathy
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
diffuse light reflex ... lesions in the inner ... ophthalmology #diagnosis ... #signs #symptoms ... #complications
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
Stevens-Johnson syndrome ... following alcohol binge ... injury (by acid reflux ... promote esophageal reflux ... melena - Other GI symptoms
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... : • Triad of symptoms ... urine • Other symptoms ... HAGMA • Late complication ... fluid/Lactated ringers
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... and signs below ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes ... #neurology #differential