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differential hematology causes workup 4ts anorexianervosa bleeding bruising comparison complications defects hemolytic hit induced inherited mds myelodysplasia myelodysplastic nonpalpable oncology
Approach to suspected Heparin-Induced Thrombocytopenia (HIT) • Suspected HIT Algorithm • "4 T's" clinical probability score:
Suspected HIT Algorithm ... (platelet count ... #HIT #hematology ... #diagnosis #4Ts ... #algorithm
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... sensorineural hearing ... #differential #diagnosis ... #hematology
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Thrombocytopenia ... - Differential Diagnosis ... Connective tissue disorders ... #Algorithm #hematology ... #platelets
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... - Differential Diagnosis ... changes), high MCV anemia ... #Platelet #Disorders ... #Differential #Diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
- Differential Diagnosis ... Algorithm Thrombocytopenia ... Sequestration Disordered ... Platelet Function ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... inflammation • Thrombocytopenia ... - Hemolytic anemia ... #Differential #Diagnosis ... #nonpalpable #dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... with or without platelet ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... • Rheumatic disorders ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Algorithm Physical ... • Factitious disorder ... • Coumadin • Heparin ... • Sickle Cell Anemia ... ulcerative #skinrash #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Algorithm Pinpoint ... hemostasis: - Thrombocytopenia ... - Abnormal platelet ... Vasculitis - Collagen disorders ... #dermatology #physicalexam
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