9 results
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Dermatological semiology of Cutaneous ... the context of cutaneous ... #dermatology #semiology ... #signs #lesions ... #diagnosis #clinical
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... nose, ears, or fingers ... presentation) • Cutaneous ... hemolytic #anemia #hematology ... #diagnosis
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... manifestations (dermatomyositis ... leukocytoclastic vasculitis ... #differential #diagnosis ... #dermatology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... aphthous ulcers, cutaneous ... episcleritis as well as inner ... purpura: strong sign ... of cutaneous leukocytoclastic
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
Cutaneous manifestations ... chest (in a V-sign ... Inverse Gottron’s sign ... #rheumatology #dermatology ... #diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... Muscle necrosis, fiber ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... of cutaneous leukocytoclastic ... episcleritis as well as inner
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Most common extra cutaneous ... Episcleritis Signs ... multiforme - Dermatomyositis ... Leukocytoclastic vasculitis ... #dermatology #oncology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... chest (in a V-sign ... shoulders (in a shawl sign ... : • ILD was diagnosed ... #rheumatology #dermatology