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Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... racemosa, Digital ulceration ... : • Behcet Disease ... #dermatology #rheumatology ... #differential #diagnosis
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
the context of cutaneous ... Connective tissue disease ... #dermatology #semiology ... #signs #lesions ... #diagnosis #clinical
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Algorithm Physical ... insufficiency • Vasculitis ... Mycosis fungoides (cutaneous ... Cryptococcosis #Ulcers #ulcerative ... #skinrash #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... aphthous ulcers, cutaneous ... episcleritis as well as inner ... purpura: strong sign ... of cutaneous leukocytoclastic
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... more): Genital ulceration ... ) • Cutaneous Lesions ... , ulcerative colitis ... #management #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... of cutaneous leukocytoclastic ... episcleritis as well as inner
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
leukocytoclastic vasculitis ... A diagnosis of pyoderma ... second most common dermatologic ... inflammatory bowel disease ... #clinical #photo
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... nose, ears, or fingers ... presentation) • Cutaneous ... hemolytic #anemia #hematology ... #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... Episcleritis Signs ... Leukocytoclastic vasculitis ... #dermatology #oncology