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differential rheumatology clinical hematology manifestations syndrome agglutinin anemia antimda5 antimda5dm antinxp2 antinxp2dm classification cold dermpath hemolytic lesions management monoclonal myelodysplastic
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... manifestations (dermatomyositis ... leukocytoclastic vasculitis ... #differential #diagnosis ... #dermatology #oncology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
the context of cutaneous ... Connective tissue disease ... #dermatology #semiology ... #signs #lesions ... #diagnosis #clinical
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... aphthous ulcers, cutaneous ... episcleritis as well as inner ... purpura: strong sign ... of cutaneous leukocytoclastic
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Cutaneous manifestations ... chest (in a V-sign ... severity of the disease ... #rheumatology #dermatology ... #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... of cutaneous leukocytoclastic ... episcleritis as well as inner
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... Episcleritis Signs ... Leukocytoclastic vasculitis ... #dermatology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... nose, ears, or fingers ... presentation) • Cutaneous ... hemolytic #anemia #hematology ... #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... gangrenosum • Cutaneous ... Sneddon-Wilkinson disease ... #Differential #Diagnosis ... #Oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... chest (in a V-sign ... had more severe disease ... : • ILD was diagnosed ... #rheumatology #dermatology
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