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rheumatology symptoms differential dermatomyositis erythematosus management oncology pathophysiology syndrome systemic antinxp2 antinxp2dm behcet chronic classification cll complications disease distribution dm
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... , Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation on skin ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Drug Associated (Commonly ... mucositis - Rash ... such as systemic lupus ... purpura: strong sign ... , and SLE) • Urinalysis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... 3rd Decade Skin ... Differential Diagnosis ... Kidney disease common
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
painless nodular rash ... wax and wane; diagnosis ... trauma leads to skin ... painless, no systemic signs ... #photo #hand
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... commonly characterize ... The signs and symptoms ... #Diagnosis #Clinical ... #Photo #Dermatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Internal organs Most common ... Episcleritis Signs ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus ... #dermatology #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... diseases, such as SLE ... purpura: Strong sign ... Nodosa: • PAN most commonly ... , mucositis • Rash
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
of age • Most common ... association • M > F Clinical ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... processes occur in the skin ... -> Heliotrope Rash ... Pathophysiology #Signs ... #Symptoms #Vasculitis
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