14 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... Trousseau's • Malignant hypertension ... anemia" • HELLP syndrome ... #diagnosis #hematology
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Primary (Essential) (95%) - Onset between age
- Differential ... taken at home, work ... excess (Cushing syndrome ... Primary #Secondary #HTN ... #Cardiology #Differential
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
Hypertensive Disorders ... Pregnancy Chronic Hypertension ... patients • HELLP: Syndrome ... of hemolysis, elevated ... #cardiology #differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... vasculitis, malignant hypertension ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... thrombocytopenic purpura/hemolytic ... uremic syndrome ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Valves, AS - HTN ... Drug-associated, PCH, Evans Syndrome ... #Differential # ... Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... for workup, including ... blood loss, Acute hemolysis ... Kawasaki, Nephrotic syndrome ... Thrombocytosis #Platelets #Differential
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
- Workup and Differential ... most pts have HTN ... White-coat syndrome ... #Workup #causes ... #Differential #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... nose, ears, or fingers ... Diagnosis: • hemolytic ... younger pts) Differential ... #anemia #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Vision changes • Hypertensive ... by 24 hours or longer ... /Hypertensive emergency ... Reversible course Differential ... • Treatment of HTN