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oncology differential msk orthopedics radiology erythematosus fracture lupus signs sle symptoms systemic treatment activation agglutinin aplastic arthritis autoimmune classification cold
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #hematology #oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
defect (rare) Raynaud's ... Demyelinating syndromes ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... reticularis • Raynaud ... nose, ears, or fingers ... anemia • Cold ... #hematology #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... #oncology #hematology ... #diagnosis #management
Distal Radius Fracture Distal radius fracture is the most common orthopedic injury. Here's a quick summary. •
carpal tunnel syndrome ... injury) • ED Management ... reduction using finger ... Colles #Distal #Radiology ... #XRay #Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Interphalangeal Joint Dislocation Interphalangeal joint dislocations almost always occur dorsally, look for associated avulsion fractures! Here's a
dislocation, due to EDS ... tendon) • ED Management ... reduction • Splint: Finger ... #XRay #Diagnosis ... #Management #Hand
Supracondylar Elbow Fracture • Most common elbow fracture in children, peak age 5-7 • When looking at
radiocapitellar lines), fat pads ... ), compartment syndrome ... • ED Management ... Elbow #Humerus #Radiology ... #XRay #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... (-) hemolytic anemia ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis
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