20 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lupus Cerebritis Induction ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Idiopathic • Infections ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Complications: 1) Infection ... transformation) Treatment ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... • Bicytopenia Treatment ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
of hands/feet, knees ... exam and imaging Treatment ... corticosteroid injections ... Arthritis #diagnosis #management ... #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... stimulation - Single fiber ... immunologic assay - MuSK ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... microglobulin Treatment ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology