43 results
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... PLEX and RTX • Short-term ... #rheumatology # ... hematology
Perilunate Dislocation
On lateral wrist XR, the capitate ("apple") should sit in the lunate ("tea cup") which
dorsally and no longer ... Disposition: Pending orthopedic ... Radiology #XRay #Diagnosis ... #Management #Orthopedics ... #Sports #MSK
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics ... Grading #Grades #Diagnosis ... #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
lesions in the inner ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
Exudates • Nerve fiber ... -> Cotton-wool spots ... of VEGF causing fine ... ophthalmology #diagnosis ... complications #pathophysiology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
validated for VTE treatment ... Bleeding #Risk #Scores ... Anticoagulation #Factors #Hematology ... #Diagnosis
Greater Trochanteric Bursa Injection 

Usually roll patient on side, find the most tender spot, approximately an
the most tender spot ... injection lasts longer ... video #procedure #rheumatology ... #sports #msk #orthopedics
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... • Weakness: Starts ... Guillain-Barre Diagnosis ... Barre #Syndrome #diagnosis ... #management #treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis ... #management #treatment
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... transfusion • Pathophysiology ... : No • Treatment ... #diagnosis #comparison