29 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... #Glomerular #Diseases ... #Proteinuria #Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Nephritic #Nephrotic ... Comparison #Algorithm #Nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... and concentrated urine ... Advanced kidney disease ... tubulointerstitial nephritis ... edgarvlermamd - Nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... chronic kidney diseases ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... also be seen if urine ... ” - Necrotic tubular ... contamination #Urine ... key #diagnosis #nephrology
Intrinsic Renal Disease - Differential Diagnosis
Vascular:
 • Macrovascular: Renal artery occlusion, Fibromuscular disease
 • Microvascular: TTP/HUS,
Intrinsic Renal Disease ... Glomerular: • Nephrotic ... Amyloidosis, MPGN • Nephritic ... Antibiotics, NSAIDs, Cast ... #nephrology #differential
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
approach to kidney disease ... urine sediment ... , WBC casts) especially ... Non-LN Kidney Disease ... algorithm #sle #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
arbitrarily defined as urine ... cell/white cell casts ... impairment), heart disease ... urine sediment ... #syndrome #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... RBCs and/or RBC casts ... • Thin GBM disease ... • Pauci-immune disease ... and >3.5g/day (nephrotic
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... (Dense deposit disease ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology