19 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... red - cells Non-glomerular ... also be seen if urine ... ” - Necrotic tubular ... key #diagnosis #nephrology
Intrinsic Renal Disease - Differential Diagnosis
Vascular:
 • Macrovascular: Renal artery occlusion, Fibromuscular disease
 • Microvascular: TTP/HUS,
HTN, Vasculitis Glomerular ... : • Nephrotic: ... Amyloidosis, MPGN • Nephritic ... Antibiotics, NSAIDs, Cast ... Renal #Disease #nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... edgarvlermamd - Nephrology ... Microscopy #Diagnosis #Nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... • Calculi Glomerular ... RBCs and/or RBC casts ... • Hereditary nephritis ... and >3.5g/day (nephrotic
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
arbitrarily defined as urine ... cell/white cell casts ... urine sediment ... #proteinuria #nephrotic ... #syndrome #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
WBCs, or urine ... • Evidence of glomerular ... proteinuria, RBC casts ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... immune deposits in glomeruli ... nephropathy, lupus nephritis ... anti-proteinase 3 (CPR ... Differential #Diagnosis #Nephrology