14 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... : • Thrombotic ... - Drug-induced thrombotic ... #schistocytes #differential ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... syndrome - Thrombotic ... microangiopathy: Thrombotic ... Extravascular #Causes #differential ... #diagnosis #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
- Primary Thrombotic ... Microangiopathy (TMA) - Differential ... Diagnosis Table ... Microangiopathy #TMA #hematology ... #differential #
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - Differential ... Diagnosis Table ... #Diagnosis #Table ... #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Approach to Thrombotic ... Microangiopathy (TMA) - Differential ... Haptoglobin, LDH, Urine ... Haptoglobin • ↑ Urine ... MatthewHoMD #Thrombotic
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
/HUS indicates thrombotic ... thrombocytopenic purpura/hemolytic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... Often hard to differentiate ... testing for TTP #Thrombotic ... Comparison #Diagnosis #Table ... #Hematology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
of Excretion: Urine ... Post-partum, ICH/TBI, Hemoptysis ... venous & arterial thrombotic ... #Pharmacology #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... hemorrhage and hemolysis ... intravascular hemolysis ... WBC count and differential ... Diagnosis #Workup #Hematology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Approach to the differential ... glomerulonephritis; TTP = thrombotic ... arbitrarily defined as urine ... because nephritic urine ... #Algorithm #differential