43 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... . mannitol) 3) Loop ... diuretic (e.g. ... Metolazone) 5) Potassium-sparing ... diuretics (e.g.
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
(B) Treatment algorithm ... Total loop diuretic ... maximal dose for IV loop ... following a single loop ... #CHF #Algorithm
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... Fluids Shift potassium ... renal function) - Loop ... diuretic (often ... LouLectures #Hyperkalemia
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP ... DIURETICS • Furosemide ... Chlorthalidone POTASSIUM-SPARING ... Tolvaptan #Diuretics
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Diuretic Action ... Panel A, loop diuretics ... shown in Panel C, diuretics ... binding to sodium–potassium–chloride
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... • HTN Absent: Loop ... and thiazide diuretics ... #causes #potassium
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
the Nephron - Diuretics ... Acetazolamide 2) Osmotic Diuretics ... mannitol) 3) Loop ... Diuretics (e.g. ... HCTZ) 5) Potassium-sparing
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Medications - Loop ... and thiazide diuretics ... abnormalities - Hypercalcemia ... - Hypokalemia ... - Osmotic diuresis
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Metolazone Loop ... Piretanide Potassium ... nephrology #conversion #loop
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... with hypokalemia ... High Urine Cl - Loop ... diuretics, Mg2+ ... #urine #potassium