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diagnosis nephrology differential pharmacology alkalosis chloride management metabolic urinary cardiology chf diuresis dosing excretion function halflife hyperkalemia hypokalemia k medications
Pharmacology of diuretics Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Acetazolamide, Loop ... Amiloride Site of Action ... #Pharmacology #Comparison ... #Table #HalfLife ... #Dosing #Loop #
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... or thiazide diuretics ... diuretic use, Bartter ... #causes #urinary
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm GI Losses - Gastric • Vomiting • NG suction GI
Causes of Metabolic ... Vomiting • NG suction ... tubular transport • Diuretics ... (loop/thiazide) ... #Causes
Major Segments of the Nephron and their Functions - Glomerulus - Formation of glomerular filtrate
organic acids and bases ... acid and most diuretics ... limb of Henle's loop ... limb of Henle's loop ... Pathophysiology #Tubules #Table
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... Remote use of loop ... or thiazide diuretics ... diuretic use, Bartter ... the indicated causes
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Diuretics and Agents ... +2Cl- Symport (Loop ... Kidney stones caused ... the Nonspecific Cation ... #Medications #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... only if no clear cause ... Elimination (see Table ... (IV loop diuretic ... acetazolamide) - IV loop
Causes of Hypokalemia - Differential Diagnosis Algorithm Decreased intake (rare cause in isolation) GI loss - Urine loss
Differential Diagnosis Algorithm ... Vomiting • NG suction ... contracted • Loop ... diuretics / Bartter's ... syndrome • Thiazide diuretics
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