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management pharmacology treatment diagnosis antifungal idsa candida clinical coccidioidomycosis hivaids infections infectiousdiseases antibiogram antibiotics candidiasis coccidioides cryptococcal cryptococcus fungal medications
Antifungal Azoles - Antibiotics Class Overview Mechanism: inhibit ergosterol synthesis (important component of fungal cell membranes)
- Only Fluconazole ... Fluconazole(PO or ... Azoles #Antifungal #Fluconazole
IDSA Treatment Recommendations for Cryptococcal Meningoencephalitis in Human Immunodeficiency Virus Infected Individuals Induction therapy: • AmBd (0.7–1.0
• AmBd plus fluconazole ... • Fluconazole ... flucytosine • Fluconazole ... Consolidation therapy: fluconazole ... Maintenance therapy: fluconazole
Antifungal Agents Frequently Used in Leukemia Antibiogram: • Fluconazole • Itraconazole • Voriconazole • Posaconazole • Caspofungin
Antibiogram: • Fluconazole
Antibiotics and CNS Diffusion 1. Drugs with good CNS diffusion: - Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole 2. Drugs
Fluoroquinolones, Fluconazole
Antifungal Coverage Activity Antibiogram Spectrum of action of systemic antifungal agents. Solid blocks represent species in
flucytosine; FLU = fluconazole
Algorithm for Evaluation and Treatment of Asymptomatic Candiduria Evidence for disseminated candidiasis, Unstable or neutropenic patient 1. fluconazole
neutropenic patient 1. fluconazole
Spectrum of activity for systemic antifungal agents Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
caspofungin; FLU, fluconazole
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
with intravenous fluconazole ... treated with oral fluconazole
Common Medications Known to Prolong QTc Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide Vasopressors/inotropes - Epinephrine, norepinephrine,
Antifungals - Fluconazole
IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days) Preferred
Preferred Therapy: • Fluconazole ... Preferred Therapy: • Fluconazole
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