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SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... mmol/L despite fluids ... • Pathophysiology ... CLINICAL RECOGNITION ... CLINICAL FEATURES
Osteoarthritis (OA): Clinical findings • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Osteoarthritis (OA): Clinical ... enzymes, joint fluid ... Osteoarthritis #OA #pathophysiology
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
Pathogenesis and clinical ... Incr glucose, fluid ... Na retention -> Fluid ... Syndrome #diagnosis #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... • Sub-retinal fluid ... Retinoblastoma #pathophysiology
Hydrocele: Pathogenesis and Clinical Findings Non-communicating: - Localized infection or trauma - Previous varicocelectomy or inguinal surgery
Pathogenesis and Clinical ... absorption of fluid ... of peritoneal fluid ... Accumulation of fluid ... #Hydrocele #Pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Pathogenesis and Clinical ... Treating DKA: 1) +++ fluids ... DiabeticKetoacidosis #DKA #pathophysiology
Age Related Macular Degeneration: Pathogenesis and clinical findings Photoreceptor atrophy -> Extracellular debris (drusen) from RPE atrophy/metabolism
Pathogenesis and clinical ... vessels leak serous fluid ... MacularDegeneration #pathophysiology
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
• Electrolyte/fluid ... may cause severe clinical ... Differential #Diagnosis #Pathophysiology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... Increased CSF fluid ... T2-weighted and fluid-attenuated ... Clinical Presentation ... : The clinical
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... or exudation of fluid ... #Mastoiditis #pathophysiology
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