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diagnosis management differential hematology lupus sle systemic activation alopecia cauda caudaequina cerebritis clinical cns dislocation equina gravis hair hairloss injury
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... severe disease Treatment ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... autoantibodies that will cause ... #SLE #CNS #neurology ... #rheumatology #
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Bedside: ice pack test ... /Edrophonium test ... immunologic assay - MuSK ... Myasthenia Crises ... diagnosis #management #neurology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Discoid lupus erythematosus ... , Loose anagen syndrome ... disease • Pull test ... texture at bald spots ... Differential #Diagnosis #dermatology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
- Emergency Causes ... • Provocative Tests ... absent anal wink test ... axial T1 and T2 Treatment ... #neurology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... Liver function tests ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Pinpoint-sized red spots ... skin that are caused ... characteristic feature ... #diagnosis #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... blockers had the best ... #Rheumatology # ... diagnosis #management #Dermatology
Posterior Knee Dislocation Injury Specifically, POSTERIOR KNEE DISLOCATIONS can have significant associated injury that needs unique approach
DISLOCATION: ~25% cases ... Neurologic deficit ... Neurologic injuries ... nerve injury (25%) TEST ... Posterior #Injury #msk
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 Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
hearing loss, nausea ... polychondritis usually spares ... Diagnosis: • Clinical tests ... affected tissue Treatment ... Polychondritis #rheumatology
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