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diagnosis pathophysiology differential neurology pagetsdisease pediatrics spinal spinalcord algorithm brain complications cushings disorders endocrinology genetics hypercortisolism injury praderwilli predictors syndromes
CATCH Predictors for Clinically Significant TBI - GCS Less than 15 at 2 hours post
for Clinically ... fracture - History ... exam - Any Sign ... Fracture - Large ... Injury #Diagnosis #Peds
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
cord lesions can ... Lower motor neuron symptoms ... anterior horn gray ... Vertebral burst fracture ... #syndromes #lesions
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Signs/Symptoms ... Incr Skeletal fractures ... , sleep apnea, cor ... pathophysiology #peds
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
: Clinical findings ... : • Symptoms and ... signs below the ... compression by fractured ... MCTD, Sjogren syndrome
Paget’s Disease: Pathogenesis and Clinical Findings • Incr serum CTx - marker of bone resorption •
Pathogenesis and Clinical ... • Lytic bone lesions ... , kyphosis and fractures ... pathophysiology #diagnosis #signs ... #symptoms
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Diagnosis and Clinical ... , pathological fractures ... /or MRI of the skull ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Osteoarthritis • Lytic lesions ... -> Pathologic fractures ... or the spinal cord ... radiculopathy • Skull ... #symptoms #complications
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