6 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... presents with coagulation ... child * Severe cases ... pregnancy * Severe coagulation ... #Pregnancy #TTPHUS
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... presents with coagulation ... child * Severe cases ... pregnancy * Severe coagulation ... #TTPHUS #HELLP
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... inflammation • Thrombocytopenia ... Platelet defects • Coagulation ... : - Thrombocytopenia ... - Hemolytic anemia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Microangiopathic hemolytic anemia ... intravascular coagulation ... microangiopathy: Thrombotic thrombocytopenic ... Extravascular #Causes
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... intravascular coagulation ... - Fanconi anaemia ... - Aplastic anaemia ... Purpura #Bruising #Causes
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
aches, leukopenia, thrombocytopenia ... bilirubin levels, thrombocytopenia ... No hemolytic anemia ... Including African tick typhus ... Life-Threatening Causes