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diagnosis differential hepatology causes management lfts injury transaminitis treatment disease abnormal acute autoimmune chronic cirrhosis gastroenterology hematology nafld nephrology nonalcoholic
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... HSV • Toxic: Alcohol ... Medication, Pregnancy, Alcoholic ... Hepatitis, TPN ... Causes #Acute #algorithm
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Induced Hepatitis ... Differential #Diagnosis #Algorithm
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
Hepatitis (AH) ... Possible ischemic hepatitis ... ) or metabolic liver ... Possible drug-induced liver ... #Hepatitis #AH
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Bilirubin - +/- elevation ... ALT Ratios: • Alcoholic ... Enzyme Elevation
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • NAFLD • Alcohol ... Ducts • PSC • Alcoholic ... hepatitis • Drugs
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... ALT Ratios: • Alcoholic ... Enzyme Elevation ... differential #diagnosis #algorithm
Alcoholic Hepatitis Treatment Algorithm #Alcoholic #Hepatitis #Treatment #Algorithm #Management #hepatology
Alcoholic Hepatitis ... Treatment Algorithm ... #Alcoholic # ... Hepatitis #Treatment ... #Algorithm #Management
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... can be bridge to Liver ... #Hepatitis #Management ... #Algorithm #treatment
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... , Toxic Hepatitis ... Infection (EBV/CMV), Alcoholic ... AST:ALT > 2.5 - Alcoholic ... #Patterns #Liver
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