19 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... Iron, B-12, or folate ... Reduction == Increase ... HgbA1c #Laboratory #Increase ... #Decrease #Diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... combination of: Decreased ... Deficiency • B12/Folate ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Decreased WBCs ... - Decreased/NormaI ... Infiltration - Increased ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Differential Diagnosis Algorithm ... Deficiency (Eg Causes ... TlBC > 18% • Anemia ... Differential #Diagnosis #Algorithm
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Deficiency • Decreased ... in this era • Increased ... have hemolytic anemia ... that can cause ... anticonvulsants lead to increase
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Decreased Megakaryopoiesis ... • Aplastic Anemia ... Deficiency • Folate ... Deficiency • Folate
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
Algorithm for the ... the most likely cause ... recovery also causes ... an elevation in ... #VitaminB12 #Folate
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Differential Diagnosis Algorithm ... Malabsorption • Increased ... Rule out B12 and Folate ... #Causes #Hematology
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Increased hepcidin ... Decreased hepcidin ... increased GI absorption ... Sideroblastic anemia ... extreme ferritin elevation
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... in most cases; ... result in severe anemia ... immune hemolytic anemia ... Mild-to-moderate elevation