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diagnosis hepatology causes lfts dermatology transaminitis abnormal disease gastroenterology generalized hematology hepatitis laboratory lactate pruritus secondary systemic workup acidosis aflp
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Findings in Hepatic / Liver ... Failure - Elevated ... ALT and AST - Elevations ... creatinine and ... BUN and a normal creatinine
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase ... - Causes of Elevated ... Levels Acute CK Elevation ... #Kinase #Elevated ... #CK #differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... Highest • Bone • Liver ... #Differential # ... Diagnosis #Algorithm
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... Syndrome (Hemolysis, Elevated ... to 10-20-fold elevation ... hepatitis #comparison #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... specificity to elevated ... Enzyme Elevation ... #diagnosis #algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
specificity to elevated ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation ... chemistry #diagnosis #differential
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Hyperbilirubinemia - Differential ... Diagnosis Algorithm ... Definition: T.bili elevation ... MRCP, ERCP, liver ... #Diagnosis #Algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... Diabetes Mellitus Liver ... • Cholestatic liver ... disease Creatinine ... #Diagnosis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... #LiverEnzymes #Differential ... #Diagnosis #Algorithm
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