24 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
== Decreased RBC ... • Asplenia Laboratory ... End-stage renal disease ... #Diagnosis #DM2 ... #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity is the diagnostic ... hallmark for the disease ... Mild-to-moderate elevation ... WBC count and differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Hyperferritinemia, decreased ... fraction < 20% Differential ... Diaqnoses: • ... #diagnosis #management
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... without platelet decrease ... bartonella (oroya fever ... #Diagnosis #Algorithm
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... ALT and AST - Elevations ... chronic liver disease ... Hepatic #Hepatology #Laboratory ... #Diagnosis #Testing
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm

Excessive Uterine Activity:
 • Hyperstimulation
 • Placental
Oxygenation - Differential ... Diagnosis Algorithm ... • Respiratory disease ... Conditions: • Fever ... #Diagnosis #Algorithm
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... myocarditis, rheumatic fever ... Idiosyncratic LDH Elevation ... #diagnosis #Laboratory
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
Laboratory Evaluation ... high; increased; decreased ... sedimentation rate normal; decreased ... #hyperthyroid #differential ... #diagnosis #endocrinology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Fragility: • Decreased ... mountain spotted fever ... #Diagnosis #hematology
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... old on day ≥7 of fever ... anemia for age, elevation ... lack of tapering, decreased ... #Diagnosis #Peds