18 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False Elevation ... == Decreased RBC ... • Asplenia Laboratory ... HbA1c #HgbA1c #Laboratory ... Diagnosis #DM2 #Differential
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... Liver Failure - Elevated ... synthesis - Elevated ... ALT and AST - Elevations ... Hepatic #Hepatology #Laboratory
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Normal or slightly elevated ... Mild-to-moderate decrease ... Mild-to-moderate elevation ... WBC count and differential
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
or normal) • Elevation ... • Expected: Elevated ... • Decreases due ... • Elevated as ... diagnosis #hematology #laboratory
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... myocarditis, rheumatic fever ... Idiosyncratic LDH Elevation ... #differential # ... diagnosis #Laboratory
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Hyperferritinemia - Differential ... Decreased hepcidin ... saturation to differentiate ... inflammatory causes of elevated ... extreme ferritin elevation
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
Laboratory Evaluation ... some cases, T3 is elevated ... ; TRAbs or TSI elevated ... high; increased; decreased ... #hyperthyroid #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate Elevation ... Lactic Acidosis - Differential ... - assess other laboratory ... muscle use • Decreased ... #Differential #
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
Dermatomyositis • Fever ... • Blood tests: Elevated ... no significant elevation ... or GGT, without elevated ... ILD worsens Decreased
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
• Headache • Fever ... pleocytosis • A mildly elevated ... /L) • Mildly decreased ... pleocytosis with an elevated ... meningeal signs (fever