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diagnosis hepatology liver lfts hematology transaminitis aa acid alveolar arterial bilirubin causes chemistry conjugated endocrinology enzymes gastroenterology gerd gradient hepatitis
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs) Elevation ... vs bone Bili - Direct ... Obstructive) vs Indirect ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Hyperbilirubinemia - Differential ... Diagnosis Algorithm ... Definition: T.bili elevation ... Hyperbilirubinemia #direct ... #Diagnosis #Algorithm
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... function panel, Direct ... hemosiderin • PT/aPTT normal ... #Diagnosis #Management
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
levels - Usually normal ... products or D-dimer - Normal ... platelet number Direct ... Mild-to-moderate elevation ... WBC count and differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... life: 1 week • Direct ... or amyloid: • Elevation ... of Liver Enzyme Elevation ... chemistry #diagnosis #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Bilirubin - +/- elevation ... Half-life: 1 week • Direct ... of Liver Enzyme Elevation
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... magnitude of enzyme elevation ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
/0.8)] - PaO2 Normal ... A-a gradient to normal ... PiO2: Extreme Elevation ... • Diffusion Defect ... Hypoxia #hypoxemia #differential
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Diagnosis and Management ... sunlight), ↓ Intake (diet ... (phenytoin) • NORMAL ... endocrinology #differential ... #algorithm
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... ULN • AST/ALT Elevation ... Direct myoglobin ... #Diagnosis #Management
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