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diagnosis liver differential algorithm hematology hepatitis lfts interpretation laboratory transaminitis aflp aih autoimmune chemistry coagulation comparison dic disease disseminated electrophoresis
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs) Elevation ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation ... Transaminitis #diagnosis #hepatology
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Algorithm • Normal ... #Pulmonary #FunctionTests
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
to 10-20-fold elevation ... Hepatic imaging: Normal ... • Histology: Normal-mild ... to 10-20-fold elevation ... Disease #Pregnancy #hepatology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Expected: Low (or normal ... ) • Elevation ... factors, Can be normal ... clots, Can be normal ... Scoring #diagnosis #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... - If both are normal ... or amyloid: • Elevation ... of Liver Enzyme Elevation ... #differential #Hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... initial response to abnormal ... magnitude of enzyme elevation ... *Abnormal USS may ... #Algorithm #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Bilirubin - +/- elevation ... - If both are normal ... function may be abnormal ... of Liver Enzyme Elevation ... diagnosis #algorithm #hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
ALT and AST - Elevations ... rapid decline to normal ... and AST can be normal ... elevated BUN and a normal ... LiverFailure #Hepatic #Hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
levels - Usually normal ... products or D-dimer - Normal ... Mild-to-moderate elevation ... Diagnosis #Workup #Hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
upper limit of normal ... (rare) - IgG Elevation ... Diagnosis #Management #Hepatology
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