17 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... Hepatocellular injury ... 2: Cholestatic injury ... #FunctionTest # ... LFTs #Elevation
Pulmonary Function Tests (PFTs) - Interpretation Algorithm
 • Normal
 • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia
 • Chest
Interpretation Algorithm ... • Normal • ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... function may be abnormal ... Enzyme Elevation ... #injury #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Bilirubin - +/- elevation ... Chronic viral hepatitis ... Enzyme Elevation
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... , Toxic Hepatitis ... #Patterns #Liver ... #Injury #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... • Infectious: Hepatitis ... NAFLD, Autoimmune hepatitis ... #Injury #Differential ... Causes #Acute #algorithm
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injuryliver ... • Infections: Hepatitis ... Diagnosis #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
to 10-20-fold elevation ... Hepatic imaging: Normal ... • Histology: Normal-mild ... to 10-20-fold elevation ... hepatology #obstetrics #hepatitis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... injury, though ... upper limit of normal ... (rare) - IgG Elevation