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diagnosis hepatology differential lfts algorithm alp chemistry enzymes hepatocellular phosphatase abnormal alkphos astalt bilirubin cholestatic fever hepatitis hyophosphatasia infectiousdiseases injury
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... Transaminase >> Alkaline ... #FunctionTest # ... LFTs #Elevation ... #Transaminitis #
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Injury • AST/ALT elevation ... + ULN ALT) / (alkaline ... phosphatase + ULN alkaline ... #Cholestatic #Transaminitis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... disturbance (obstructed liver ... Bone growth) Alkaline ... Highest • Bone • Liver ... stricture/Stones #Alkaline
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... compared with alkaline ... disproportionate increase in alkaline ... hepatology #algorithm #Transaminitis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... Tests - AST, ALT, Alkaline ... In liver, 80% of ... Alkaline phosphatase ... hepatocyte - Elevation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation ... differential #Hepatology #transaminitis
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... derangement of liver ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Low Alkaline Phosphatase ... Hypophosphatasia Is Low Alkaline ... synthesized in: liver ... eliminated • Elevation ... phosphate &/or • Elevation
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
aminotransferase and alanine ... febrile illness, elevations ... including tests of liver
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