23 results
diagnosis hepatology differential lfts transaminitis hepatitis injury dermatology management abnormal aflp alkaline enzymes gastroenterology generalized hepatocellular obstetrics phosphatase pregnancy primary
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... ≥ 3x ULN Cholestatic ... pattern ≤2: Cholestatic ... #FunctionTest # ... LFTs #Elevation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
RNA • R < 2: Cholestasis ... Bilirubin - +/- elevation ... of cholestatic ... or amyloid: • Elevation ... Enzyme Elevation
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
) - Causes of Hepatocellular ... and Cholestatic ... • AST/ALT elevation ... Hepatocellular or Cholestatic ... R ≤ 2 = Cholestatic
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Bilirubin - +/- elevation ... Enzyme Elevation ... differential #diagnosis #algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... Intestine - Other causes ... #Diagnosis #Algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... or AST > ALP): ... def, Wilson's, Cholestatic ... dz Cholestatic
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Others • Cholestatic ... Differential #Diagnosis #Algorithm ... #Causes
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Differential Diagnosis Algorithm ... Definition: T.bili elevation ... = intrahepatic cholestasis ... non-ICU vs ICU causes ... MRCP, ERCP, liver
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Thrombus, Vasospasm Cholestatic ... Hepatitis, TB Cholestatic ... Differential #Diagnosis #Causes ... #Acute #algorithm
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Intrahepatic Cholestasis ... to 10-20-fold elevation ... Histology: Normal-mild cholestasis ... to 10-20-fold elevation ... of Pregnancy (AFLP
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