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diagnosis differential hematology hepatology secondary abnormal aptt coagulation generalized prolonged pruritus pt acidosis acute bilirubin bleeding bruising classification conjugated gastroenterology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... vs bone Bili - Direct ... #FunctionTest # ... LFTs #Elevation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Disease Vascular System ... Iatrogenic) • Liver ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Primary Causes ... • Cholestatic liver ... #generalized #dermatology ... #causes
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Differential Diagnosis Algorithm ... Definition: T.bili elevation ... non-ICU vs ICU causes ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Drugs: Direct or ... drugs (e.g. direct ... • Reduced liver ... associated with systemic ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Direct or indirect ... Reduced liver synthesis ... associated with systemic ... #differential #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Bilirubin - +/- elevation ... Half-life: 1 week • Direct ... Enzyme Elevation
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... discoloration) • Liver ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... by cells as a direct ... Elevation Type ... of Circulatory System ... Lactic #Acidosis #Elevation
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diabetes Mellitus Liver ... • Cholestatic liver ... Pruritus #secondary #systemic ... #generalized #dermatology ... #causes
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