18 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... Hepatocellular injury ... 2: Cholestatic injury ... #FunctionTest # ... LFTs #Elevation
Pulmonary Function Tests (PFTs) - Interpretation Algorithm
 • Normal
 • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia
 • Chest
Interpretation Algorithm ... • Normal • ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... function may be abnormal ... Enzyme Elevation
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Bilirubin - +/- elevation ... - If both are normal ... or amyloid: • Elevation ... of ALP • Near normal ... Enzyme Elevation
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... magnitude of enzyme elevation ... #Algorithm #Hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... dose dependent injury ... differential #Diagnosis #Management ... gastroenterology #algorithm
C-REACTIVE PROTEIN
Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
synthesized by the liver ... than 0.3 mg/L: Normal ... 0.3 to 1.0 mg/L: Normal ... or minor elevation ... Recent injury or
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... injury, though ... upper limit of normal ... (rare) - IgG Elevation
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Diagnosis and Management ... - Activation: Liver ... (phenytoin) • NORMAL ... Hypocalcemia #Diagnosis #Management ... #differential #algorithm
Mild-to-Moderate Ulcerative Colitis - Management Algorithm
Curcumin:
 • Natural phytochemical from turmeric
 • 2g/day divided in 2-3
Ulcerative Colitis - Management ... Potential GI SE, liver ... injury, inhibit ... decreased dosing if liver ... #Colitis #UC #Management