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diagnosis hepatology lfts transaminitis enzymes hepatitis abnormal aflp alkaline alp bilirubin chemistry comparison conjugated ddxof direct disease dysphagia em esophageal
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... ALT ≥ 3x ULN Cholestatic ... pattern ≤2: Cholestatic ... #FunctionTest # ... LFTs #Elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... - Differential ... Other causes of elevation ... consult ALP elevation ... Phosphatase #ALP #Elevation
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Hepatocellular and Cholestatic ... • AST/ALT elevation ... Hepatocellular or Cholestatic ... R ≤ 2 = Cholestatic ... Transaminitis #diagnosis #differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
RNA • R < 2: Cholestasis ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation ... chemistry #diagnosis #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Bilirubin - +/- elevation ... Enzyme Elevation ... #diagnosis #algorithm
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Diagnosis Algorithm ... Definition: T.bili elevation ... = intrahepatic cholestasis ... MRCP, ERCP, liver ... #Diagnosis #Algorithm
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Intrahepatic Cholestasis ... to 10-20-fold elevation ... Histology: Normal-mild cholestasis ... to 10-20-fold elevation ... hepatitis #comparison #differential
Algorithm for the Evaluation of Dysphagia:Oropharyngeal: - Characterized by difficulty initiating swallowing and accompanied by choking/coughing, nasopharyngeal
Algorithm for the ... , soft palate (elevation ... medulla #Diagnosis #Differential ... #Extraluminal #Algorithm ... #Differential #
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... magnitude of enzyme elevation ... LFTs #Abnormal #Algorithm ... #Enzymes #Differential
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