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diagnosis differential hematology prolonged pt bruising anemia classification dic disorders disseminated genital gynecology hemostasis hepatitis hepatology injury inr intravascular management
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT, Normal PT ... (INR) - Bleeding ... Differential #Diagnosis #Algorithm ... #coagulation #disorders
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Treat primary cause ... INR < 2.3 - APTT ... < 1.5 x normal ... #diagnosis #causes
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Causes #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Pre-analytical cause ... Reduced liver synthesis ... Jcortesizaguirr #Abnormal
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... /NORMAL PTT: Suggests ... PT/ABNORMAL PTT ... discern these causes
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... • Reduced liver ... amyloidosis #Abnormal ... differential #hematology #coagulation
Causes of Abnormal Genital Bleeding - Differential Diagnosis Algorithm Non-Gynecologic: • Medical (e.g. coagulopathy, liver disease, renal
Causes of Abnormal ... Genital Bleeding ... Differential Diagnosis Algorithm ... coagulopathy, liver ... #Causes #OBGyn
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease Normal ... 80-100 fL) • Bleeding ... Renal Disease, Liver ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... function may be abnormal ... RBC (hemolysis, bleeding ... differential #diagnosis #algorithm
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