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diagnosis differential causes hepatology management secondary dermatology gastroenterology injury lfts pruritus systemic transaminitis abdominal generalized hyponatremia interpretation nephrology pediatrics peds
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... abnormality vs bone Bili ... SinaiBmoreIMRes #Liver ... #FunctionTest #
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... presentation • Chronic ... or symptoms of liver ... Drug #induced #Liver ... gastroenterology #algorithm
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... dechallenge • Acute or chronic ... e.g. ascites), Chronic ... Injury #Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... • Iatrogenic: DILI ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... differential #diagnosis #algorithm
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... disease, liver ... Injury (DILI) ... #ACLF #Acute #Chronic
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Cirrhosis • Chronic ... (>1000): • DILI ... (Drug-induced liver ... LouLectures #Liver
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
The Liver Consult ... Focus on prior Liver ... GTT, indirect bili ... current MELD - Chronic ... up - Liver US
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... Unconjugated Bili ... > 90% of Total Bili
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... • Anemia of Chronic ... Renal Disease, Liver ... Reticulocytosis • Liver ... Differential #Diagnosis #Algorithm
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