10 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
(INR) - Bleeding ... (INR) - No Bleeding ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... DrEricStrong #Algorithm ... #Coagulation #Abnormal ... APTT #Laboratory #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Causes #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... Jcortesizaguirr #Abnormal ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... Thrombocytopenia - Normal ... DIC • Severe Liver ... - APTT < 1.5 x normal ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... PT/ABNORMAL PTT ... the PT remains prolonged ... intravascular coagulation ... Differential #Diagnosis #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... Chronic Disease Normal ... 80-100 fL) • Bleeding ... Renal Disease, Liver ... #Causes #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... • Reduced liver ... amyloidosis #Abnormal ... #differential #hematology ... #coagulation
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- If both are normal ... • Albumin • Coagulation ... of ALP • Near normal ... RBC (hemolysis, bleeding ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... function may be abnormal ... RBC (hemolysis, bleeding ... differential #diagnosis #algorithm ... #hepatology