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diagnosis causes coagulation aptt bruising hepatology anemia chemistry classification dic disorders disseminated hemostasis hepatitis injury inr interpretation intravascular lfts management
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PT (INR), Normal ... PTT, Normal PT ... Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... #PT #aPTT #Prolonged ... Causes #diagnosis #differential ... #hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... ) ABNORMAL PT ... prolonged after ... PT/ABNORMAL PTT
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged ... #hematology #coagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Diagnosis Algorithm ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Chronic Disease Normal ... 80-100 fL) • Bleeding ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... treatment #management #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
- If both are normal ... Coagulation factors: PT ... RBC (hemolysis, bleeding ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... function may be abnormal ... RBC (hemolysis, bleeding ... #hepatology
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