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diagnosis hepatology differential lfts interpretation transaminitis hepatitis management tests abnormal alcoholic causes chemistry drug druginduced enzymes gastroenterology heat heatstroke idiosyncratic
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... abnormality vs bone Bili ... #FunctionTest # ... LFTs #Elevation
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Pulmonary Function ... Interpretation Algorithm ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... Tests of synthetic function ... Enzyme Elevation
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... or symptoms of liver ... Drug #induced #Liver ... gastroenterology #algorithm
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... involvement, Kidney injury ... #Injury #Diagnosis ... #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic ... #Function #Tests
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation ... Unconjugated Bili ... > 90% of Total Bili
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... nucleotidase - Liver ... bilirubin (Conjugated/DBili ... hepatocellular injury ... #Function #Tests
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... derangement of liver ... magnitude of enzyme elevation ... LFTs #Abnormal #Algorithm
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
sweat Heat Injury ... Muscles, Kidneys, Liver ... injury, Rhabdomyolysis ... Loss of muscle function ... acidosis - CPK elevation
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