15 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... Transaminase >> Alkaline Phosphatase ... Pattern - Alkaline Phosphatase ... #FunctionTest # ... LFTs #Elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
(ALP) Elevation ... Differential Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... #ALP #Elevation
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... elevation > Alk ... phosphatase + ULN ... alkaline phosphatase
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Of Clinical Importance ... synthesized in: liver ... is critical for ... eliminated • Elevation ... &/or • Elevation
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... , Alkaline Phosphatase ... : • AST: liver ... Alkaline phosphatase ... hepatocyte - Elevation
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... Enzyme Elevation ... differential #diagnosis #algorithm
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... /or suspicious clinical ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... LFTs #Abnormal #Algorithm
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
increase in AST/ALT ... with alkaline phosphatase ... increase in alkaline phosphate ... compared with AST/ALT ... Diagnosis #hepatology #algorithm
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... to 10-20-fold elevation ... post-partum • Typical clinical ... to 10-20-fold elevation ... of Pregnancy (AFLP
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis Clinical ... Highly variable clinical ... disease to acute liver ... hepatocellular pattern of liver ... (rare) - IgG Elevation