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diagnosis hepatology lfts algorithm causes transaminitis aflp alkaline alp bilirubin chemistry enzymes fever hepatitis infectiousdiseases laboratory lactate management obstetrics phosphatase
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... #Differential #
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... Injury • AST/ALT elevation ... Transaminitis #diagnosis #differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation ... chemistry #diagnosis #differential
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... to 10-20-fold elevation ... Hemolysis, Elevated Liver ... to 10-20-fold elevation ... hepatitis #comparison #differential
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... ALT: • AST: liver ... In liver, 80% of ... hepatocyte - Elevation ... Bilirubin #Hepatology #Pathophysiology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Bilirubin - +/- elevation ... Enzyme Elevation ... injury #hepatitis #differential
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Hyperbilirubinemia - Differential ... Definition: T.bili elevation ... MRCP, ERCP, liver ... direct #bilirubin #Differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... hepatocytes → Liver ... infiltration) Differential ... diagnosis #management #pathophysiology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... response to abnormal liver ... derangement of liver ... magnitude of enzyme elevation ... #Enzymes #Differential
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