13 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Destruction • Abnormal ... Iatrogenic) • Liver
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
dysfunction (25%) • Hepatic ... DIC • Severe Liver ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... - APTT < 1.5 x normal
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PT (INR) - Bleeding ... PT (INR) - No Bleeding ... #PPT #PT #INR #Differential ... #Diagnosis #Algorithm ... Causes #Hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor of a coagulation ... Acquired: • Heparin ... intravascular coagulation ... Bruising #Hemostasis #Differential
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Bleed - Management Algorithm ... GI Bleed: • Peptic ... Disease • Variceal Bleeding ... GAVE (idiopathic, liver ... UGIB #GIBleed #Differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... RBC (hemolysis, bleeding
Causes of Abnormal Genital Bleeding - Differential Diagnosis Algorithm
Non-Gynecologic:
 • Medical (e.g. coagulopathy, liver disease, renal
Causes of Abnormal ... Genital Bleeding ... - Differential ... Diagnosis Algorithm ... coagulopathy, liver
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Chronic Disease Normal ... 80-100 fL) • Bleeding ... Renal Disease, Liver
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... Jcortesizaguirr #Abnormal ... Causes #diagnosis #differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- If both are normal ... • Albumin • Coagulation ... replaced by non-hepatic ... RBC (hemolysis, bleeding ... chemistry #diagnosis #differential