29 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... Sepsis, Viral Hepatitis ... Causes #Acute #algorithm
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... • Autoimmune ... Hepatitis • Drug ... Differential #Diagnosis #Algorithm
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Common Etiologies ... Inflammation - Hepatitis ... 15 percent) - Hepatitis ... Schistosomiasis - Autoimmune ... Nonalcoholic fatty liver
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Ischemia • Autoimmune ... • Alcoholic hepatitis ... Bile Ducts • Common
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... disease to acute liver ... arthralgias) are common ... Muscle Abs (ASMA) (common ... (eg Viral) Management
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... Diagnosis and Management ... Algorithm • ... #HBV #Algorithm ... #Diagnosis #Management
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Non-specific; common ... in SLE, autoimmune ... hepatitis Anti-CCP ... Dermatomyositis Anti-LKM (liver ... microsomal) - Autoimmune
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... • Infections: Hepatitis ... Other: NAFLD, Autoimmune ... Diagnosis #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... Alcohol, Viral hepatitis ... , Autoimmune • ... (VIII is most common ... - Malignancy, Autoimmune
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
Disease - Diagnosis Algorithm ... treatment • Elevated liver ... Individuals with autoimmune ... thyroiditis, hepatitis ... Celiac disease • Autoimmune