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diagnosis differential hepatology lfts cirrhosis injury primary abnormal anemia dermatology elevation generalized hematology pruritus secondary systemic transaminitis acute acutekidneyinjury aki
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary Biliary ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... ALP - Biliary ... SinaiBmoreIMRes #Liver ... #FunctionTest #
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... hepatitis, Acute biliary ... Malignancy, 1° PBC ... Extrahepatic • Biliary ... #Acute #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Extrahepatic - Biliary ... stone, Malignancy, PBC ... differential #diagnosis #algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Highest • Bone • Liver ... Intestine - Other causes ... Cholangitis (PBC ... - Other biliary
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Pathophysiology ... intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... or higher • Liver
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... Liver biopsy findings ... #Biliary #Cirrhosis ... #Diagnosis #Algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... Ducts - PBC ... - CBD stone, Biliary ... Transaminitis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Bile Ducts • PSC ... Duct Stone • Biliary ... #Causes
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
Causes of Fat Malabsorption ... Differential Diagnosis Biliary ... • Autoimmune— PBC ... — liver fluke, HIV ... Differential #Diagnosis #Causes
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